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aaron g rosenberg[Author]
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Engineering the T cell receptor for fun and profit: Uncovering complex biology, interrogating the immune system, and targeting disease.
Curr Opin Struct Biol. 2022 Jun;74:102358. doi: 10.1016/j.sbi.2022.102358. Epub 2022 Mar 25.
Curr Opin Struct Biol. 2022.
PMID: 35344834
Free PMC article.
Review.
Enhanced T cell receptor specificity through framework engineering.
Rosenberg AM, Ayres CM, Medina-Cucurella AV, Whitehead TA, Baker BM.
Rosenberg AM, et al.
Front Immunol. 2024 Mar 12;15:1345368. doi: 10.3389/fimmu.2024.1345368. eCollection 2024.
Front Immunol. 2024.
PMID: 38545094
Free PMC article.
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A class-mismatched TCR bypasses MHC restriction via an unorthodox but fully functional binding geometry.
Singh NK, Alonso JA, Devlin JR, Keller GLJ, Gray GI, Chiranjivi AK, Foote SG, Landau LM, Arbuiso AG, Weiss LI, Rosenberg AM, Hellman LM, Nishimura MI, Baker BM.
Singh NK, et al. Among authors: rosenberg am.
Nat Commun. 2022 Nov 23;13(1):7189. doi: 10.1038/s41467-022-34896-0.
Nat Commun. 2022.
PMID: 36424374
Free PMC article.
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An Engineered T Cell Receptor Variant Realizes the Limits of Functional Binding Modes.
Singh NK, Alonso JA, Harris DT, Anderson SD, Ma J, Hellman LM, Rosenberg AM, Kolawole EM, Evavold BD, Kranz DM, Baker BM.
Singh NK, et al. Among authors: rosenberg am.
Biochemistry. 2020 Nov 3;59(43):4163-4175. doi: 10.1021/acs.biochem.0c00689. Epub 2020 Oct 19.
Biochemistry. 2020.
PMID: 33074657
Free PMC article.
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